Can you take fioricet and adipex together?

Now, if you are talking about taking them both at the same time, NO. You would be defeating the purpose of both drugs. You should take the Phentermine in the AM and of course at least 12 hours later, depending on the dose of the Phentermine, you can then take the Ambien to go to sleep, since sometimes the Phentermine can make it impossible to go to sleep at a normal hour.