What is the degree of damage rabies cause to humans?

Rabies is a viral infection that affects the central nervous system and is almost universally fatal once clinical symptoms appear. The disease can cause severe neurological symptoms, including confusion, agitation, paralysis, and hydrophobia, leading to coma and death within weeks of symptom onset. Prevention through vaccination after exposure is critical, as there is no effective treatment once symptoms manifest. Early intervention is crucial to prevent irreversible damage and ensure survival.