Chemical digestion occurs primarily in the stomach and small intestine for all macromolecule types. Proteins are broken down by gastric acids and enzymes in the stomach and further digested by pancreatic enzymes in the small intestine. Carbohydrates begin their chemical digestion in the mouth with saliva and continue in the small intestine with pancreatic amylase. Fats are emulsified by bile in the small intestine and digested by pancreatic lipase.
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