Yes... i had a decaying molar and when the pain got so severe i decided to try to find a painkiller to take. All I could find was methadone and being so desperate for pain relieve, I took one pill (not sure of dosage). it worked quite well for the pain but it also cured it! I awoke the next morning and there was still no pain. I soon realized that the tooth partially grew out.
This happened more than 6 months ago and although my tooth continued to fall apart, the pain never returned!!
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