Can bactrim give a false negative urine?

Yes, Bactrim (sulfamethoxazole and trimethoprim) can potentially cause false negative results in urine drug tests, particularly for substances like methamphetamine and some other drugs. This is due to the drug's chemical structure, which may interfere with the testing assays. However, it's important to note that the likelihood of false negatives can vary based on the specific test used and its sensitivity. Always consult with a healthcare professional for accurate interpretations of test results.