How long does it take to get from Reading to Liverpool by train?

May be more than one route. The obvious is via London but are there any services via, e.g. Poole / Bournemouth or Bristol that may be quicker or more convenient?

You should be able to work it out from the National Rail Enquiries & similar web-sites, as with (your?) other question about Weymouth - London fare, but even finding Upwey to Wool details proved an exercise in Advanced IT!

If you don't mind long bus journeys & the times are right for you I believe there is a National Express Weymouth - Blackpool service that if it doesn't go via Liverpool may drop you at a convenient bus-station in the area.