What effect does estrogen cream have on a man's penis?

Estrogen cream can have several effects on a man's penis, primarily related to hormonal balance. When applied, it may lead to changes in tissue sensitivity and vascular function, potentially affecting libido and erectile function. Long-term use could also result in feminization effects, such as decreased testosterone levels and changes in penile tissue. It's essential for men to consult a healthcare professional before using estrogen or any hormone therapy.