What was the name of the first attempt by England to start a colony it was unsuccessful and the colonists dissappeared to this day we are still not sure what happen to them?

The first attempt by England to establish a colony in the New World was the Roanoke Colony, founded in 1585 on Roanoke Island, off the coast of present-day North Carolina. The colony struggled for resources and support, and when a supply ship returned in 1590, the settlers had vanished without a trace, leaving behind the mysterious Word "CROATOAN" carved into a tree. The fate of the colonists remains an enduring mystery, with various theories but no definitive answers.