Will a 5x110 fit a 5x114 wheel?

No, a 5x110 wheel will not fit a 5x114 hub because the bolt patterns are different. The numbers represent the number of bolts and the distance in millimeters between the centers of the bolts. Since the spacing is not compatible, using a 5x110 wheel on a 5x114 vehicle would not be safe or feasible without adapters, which may not always ensure proper fitment.