No. To begin with, platypuses have no teeth so they cannot bite.
However, the male platypus does have the distinction of being one of the world's most venomous mammals. This creature has a small, hollow, poisonous spur on the back of each of its hind feet. The venom cannot kill a person, but it will cause swelling and excruciating pain that can last for months. The venom is enough to kill an animal the size of a small dog, but not a healthy human.
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