What causes granuloma in the lungs?

Granulomas in the lungs are typically caused by an inflammatory response to various irritants or infections. Common causes include infections like tuberculosis and fungal diseases, as well as non-infectious factors such as autoimmune diseases, environmental exposures (like silica or asbestos), and certain medications. The body's immune system attempts to isolate and contain these irritants, leading to the formation of granulomas, which are clusters of immune cells. This process can result in lung tissue damage and impaired function if not resolved.