Why must someone be selective when choosing which cell to use to make a karyotype?

When creating a karyotype, it is essential to be selective in choosing cells because not all cells are in the appropriate stage of division for chromosome visualization. Typically, cells in the metaphase stage of mitosis are ideal since the chromosomes are condensed and easily distinguishable. Additionally, selecting cells from tissues that reflect the organism's genetic makeup is crucial for accurate analysis. Using the wrong type of cell or stage can lead to misinterpretations of chromosome number or structure.