Is it safe to take 25 mg. of doxylamine succinate and 440 mg of acetaminophen?

I've worked in pharmacy for awhile.

There is no know interaction between the too. However to be on the safe side do not take anymore than 25mg of Doxylamine Succinate and take a regular does of ibuprofen NOTHING with added codeine in it!

As one is an anti-inflamatory and the other is a calmative it MAY slightly increase the "hungover" feeling the next day. Personally I find a bit of caffeine helps make that go away but it depends on the individual!