What is the difference between microfiber sheets and Egyptian cotton sheets?

Microfiber is woven very tight, nice silk like texture (good for summer) and Egyptain cotton is a bit heavier soft and I perferr it in the winter it tends to keep the heat in, both are really good just get a high thread count above 1000.

Keep in mind that microfiber sheets are made of polyester and nylon polymers. Microfiber has a synthetic feel to it and the similarity is analogous to polyester versus cotton clothing. The tread-count comparison to cotton is misleading because a higher count in microfiber does not improve softness the way it does with cotton sheets.