Who holds the record for the most blocks in college basketball?

In one NCAA tournament game, Shaquille O'Neal blocked 11 shots.

Single Game: Mickell Gladness, a 6-11 junior from Alabama A&M University blocked 16 shots against Texas Southern in a 79-73 victory in 2007.

Career: The all-time leader in NCAA Basketball is Jarvis Varnado. He played at Mississippi State and over a four year career (141 games) swatted 564 shots. Blocks records for NCAA ball technically started in 1986.

Number 2 is Wojciech Mydra with 535.