Very rarely.
Amtrak is the operator of inter-city train service in the United States. Greyhound is the major inter-city bus service in the United States. Occasionally they will share a station (Milwaukee for example), but usually not. There is frequently a Greyhound bus stop at an Amtrak station allowing train passengers to connect to points not served by trains. But the bus stop is usually just a street corner outside the station and the city's primary bus station is located elsewhere.
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