A burning sensation under the rib cage after drinking wine may be caused by several factors, including acid reflux or gastroesophageal reflux disease (GERD), where stomach acid flows back into the esophagus. Wine, especially red varieties, can relax the lower esophageal sphincter, allowing acid to escape. Additionally, the sulfites and tannins in wine can irritate the stomach lining in some individuals. If the sensation persists, it's advisable to consult a healthcare professional for a proper diagnosis.
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