One common problem that can cause scrotal swelling in men is Congestive Heart Failure (CHF). If you are experiencing swelling in your lower extremities and in the testicles, I would go see a cardiologist, as the problem with the testicles is not from the testicles themselves, but from a problem with the heart.
Other problems that could cause testicular swelling would be a testicular torsion (rip inside the testicle), epiditymitis (infection of the sperm duct inside the testicle), and a testicular hernia (part of the testis is protruding from the sac that surrounds them under the skin). These conditions are very painful and may require emergency attention.
One reason that could cause swelling in the testicles are tumors (cancerous). These tumors are mainly painless. However, do not be afraid, as just because you may have a tumor, it is not always the case that this tumor is malignant.
Sources: nursing student
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