Oxycodone is generally safe when taken as directed. However, there are several possible ways in which the risks of taking this medication can be exacerbated. Combining oxycodone with other opioids or depressants (alcohol, benzodiazepines, etc.) can be very dangerous and potentially can cause a life-threatening overdose. Additionally, taking more oxycodone than prescribed can also cause a dangerous overdose.
It is worth noting that if oxycodone or any opioid is taken regularly for an extended period of time, addiction and/or dependence can result. Even individuals taking the prescribed dose of this medication will likely experience withdrawal symptoms upon cessation after extended use (a couple weeks of daily use is generally sufficient to result in dependence). Of course, the higher the dose taken, the worse the withdrawal will generally be.
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