Which pair of elements is found in only one of the four types of macromolecules?

Nitrogen and phosphorus are found in only one of the four types of macromolecules. Specifically, nitrogen is a key component of nucleic acids (like DNA and RNA) and proteins, while phosphorus is primarily associated with nucleic acids and ATP. Carbohydrates and lipids do not contain these elements. Thus, the unique presence of nitrogen and phosphorus in nucleic acids distinguishes them from the other macromolecule types.