Methadone is metabolized primarily in the liver, and its metabolites may not be detected by standard drug screens, which are often designed to identify only specific substances. Additionally, the sensitivity and specificity of the drug test being used can affect whether methadone or its metabolites are detected. Some tests may not include methadone in their panel, while others may not be sensitive enough to pick up lower concentrations of the drug or its metabolites. If you're concerned, it's best to discuss this with your healthcare provider or the testing facility.
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