The two types of cell cycle genes that, when mutated, can lead to uncontrolled cell division and cancer are oncogenes and tumor suppressor genes. Oncogenes promote cell division and growth; mutations can lead to their overactivity, driving excessive proliferation. In contrast, tumor suppressor genes normally inhibit cell division or promote apoptosis; mutations can inactivate these protective functions, allowing unchecked cellular growth. Both types of mutations disrupt the delicate balance of cell cycle regulation, contributing to cancer development.
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