How far apart should you take your thyroxine and amitriptyline?

Thyroxine and amitriptyline should ideally be taken at least 4 to 6 hours apart to minimize potential interactions. Thyroxine is best absorbed on an empty stomach, so it's recommended to take it in the morning before breakfast. If you take amitriptyline in the evening, this timing should help reduce any interference with thyroxine absorption. Always consult your healthcare provider for personalized advice.