What is Factor V Lieden?

Factor V Leiden is a genetic mutation that affects the blood clotting process, specifically involving the factor V protein. This mutation makes the protein resistant to being inactivated by activated protein C, leading to an increased risk of abnormal blood clot formation, known as thrombosis. Individuals with Factor V Leiden are at higher risk for conditions such as deep vein thrombosis (DVT) and pulmonary embolism. The condition is inherited in an autosomal dominant pattern, meaning that only one copy of the mutated gene is needed to increase the risk of clotting disorders.