Will 215-65R16 work on 2001 Toyota Sienna?

Yes, 215/65R16 tires can work on a 2001 Toyota Sienna, as they are compatible with the vehicle's standard tire size. However, it's essential to ensure that the tires have sufficient clearance and do not interfere with the suspension or body. Always consult your owner's manual or a tire professional for specific recommendations and to confirm compatibility with your vehicle's specifications.