In the "House of M" storyline, the Scarlet Witch, Wanda Maximoff, uses her reality-altering powers to create an alternate universe where mutants are the dominant species and humans are the minority. This new reality is shaped by her desire for a normal life with her children, leading to the creation of a world where her father, Magneto, rules. Ultimately, the storyline culminates in the revelation of her mental instability and the catastrophic consequences of her actions, which result in the decimation of the mutant population. The phrase "No more mutants" is famously uttered, leading to the vast reduction of mutants in the Marvel Universe.
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