Why did Paul and Barnabas separate at Antioch?

Paul and Barnabas separated at Antioch due to a disagreement over whether to take John Mark with them on their missionary journey. Barnabas wanted to include John Mark, while Paul objected because Mark had previously left them during a prior mission. This sharp disagreement led to their decision to part ways, with Barnabas taking Mark to Cyprus and Paul choosing Silas as his new companion for the journey. This split allowed both pairs to continue spreading the Gospel in different regions.