What is the setting of Captain Underpants and the wrath of the wicked wedgie woman?

The setting of "Captain Underpants and the Wrath of the Wicked Wedgie Woman" primarily takes place in the fictional town of Piqua, Ohio, where the main characters, George Beard and Harold Hutchins, navigate their school environment and home life. The story unfolds at Jerome Horwitz Elementary School, particularly focusing on the interactions between students and teachers, as well as the antics that lead to the superhero Captain Underpants' adventures. The narrative is filled with imaginative elements, such as the school and various locations around town, contributing to the humor and chaos of the plot.