What is the function of Dendritic cells and macrophages in the lymph nodes?

Dendritic cells and macrophages play crucial roles in the immune response within lymph nodes. Dendritic cells act as antigen-presenting cells, capturing and processing antigens from pathogens and then presenting them to T cells to initiate an adaptive immune response. Macrophages help in phagocytosing pathogens and debris, while also presenting antigens to T cells, thereby facilitating the activation and differentiation of these immune cells. Together, they orchestrate the immune response by enhancing communication and coordination between innate and adaptive immune systems.