Can you take Zoloft with guaifenesin and DXM?

Taking Zoloft (sertraline) with guaifenesin and dextromethorphan (DXM) can be done with caution, as there are no direct contraindications. However, DXM can increase serotonin levels, which may lead to serotonin syndrome when combined with Zoloft. It's essential to consult with a healthcare provider before combining these medications to ensure safety and proper management of potential interactions. Always follow professional medical advice for your specific situation.