Why is chloroquine superior to quinine?

Chloroquine is considered superior to quinine primarily due to its improved efficacy, safety profile, and tolerability. Chloroquine has a more favorable pharmacokinetic profile, allowing for easier dosing and better absorption. Additionally, it has fewer side effects and is generally better tolerated by patients compared to quinine, which can cause more severe adverse reactions such as cinchonism. Consequently, chloroquine has become the preferred treatment for certain types of malaria.