What is the physical and mental response of narcotics?

Narcotics, or opioids, primarily bind to opioid receptors in the brain, leading to pain relief, euphoria, and sedation. Physically, they can slow down respiration, decrease heart rate, and cause drowsiness or constipation. Mentally, narcotics can induce feelings of relaxation and well-being, but they also carry a risk of addiction, dependence, and withdrawal symptoms when not used properly. Over time, their use can impair cognitive function and emotional regulation.