The primary antagonist for midazolam is flumazenil. Flumazenil is a benzodiazepine receptor antagonist that can reverse the sedative effects of midazolam and other benzodiazepines. It is commonly used in situations of benzodiazepine overdose or to counteract sedation during medical procedures. However, flumazenil should be used cautiously, as it may induce seizures in patients who are dependent on benzodiazepines.
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