What causes a f 150 to vibrate 60 to 70 mph and when you let off gas it stops?

Vibration in an F-150 at 60 to 70 mph, which alleviates when you let off the gas, is often caused by issues with the drivetrain, such as unbalanced tires, worn-out U-joints, or a misaligned driveshaft. It could also stem from problems with wheel bearings or suspension components. Additionally, tire defects or uneven wear can contribute to this problem. A thorough inspection is recommended to pinpoint the exact cause.