How does uric acid effect body parts?

Normally the body filters uric acid and it is removed with urine, however if this function is impaired in some way you end up with a situation where the uric acid turns into crystals that settle in joints usually starting with the big toe. this is an extremely painful condition that can be accompanied with severe swelling around the affected joints. the joints most likely to be affected are in the hands and feet. A diet low in purines is the first suggestion for those suffering from this condition.