Can long term use of zoloft cause low white blood count?

Long-term use of Zoloft (sertraline) is not commonly associated with causing low white blood cell counts, also known as leukopenia. However, some individuals may experience changes in blood cell counts as a rare side effect. If you have concerns about your white blood cell levels while taking Zoloft, it’s important to discuss this with your healthcare provider for appropriate evaluation and guidance.