Should seroquel be taken with food or with out food?

Seroquel (quetiapine) can be taken with or without food; however, taking it with food may help reduce the risk of gastrointestinal side effects. It's important to follow your healthcare provider's instructions regarding how to take the medication. Consistency in how you take it (either always with food or always without) can help maintain stable levels of the drug in your system. Always consult your doctor or pharmacist if you have specific questions about your medication regimen.