Who was the US leader who defeated Santa Ana?

The U.S. leader who defeated Santa Anna was General Sam Houston. He commanded the Texian Army during the Battle of San Jacinto on April 21, 1836, where his forces achieved a decisive victory against Santa Anna's Mexican troops. This victory was pivotal in securing Texas independence from Mexico. Santa Anna was captured shortly after the battle, which helped solidify Houston's reputation as a key figure in Texas history.