What are the long term effects of tobacco use?

carbon monoxide inhaled in cigarette smoke resonates with depression.

smoking depletes you of vitamin C , so increase in wrinkles because you need vitamin c to make collagen.

Nicotine is an acid, it makes you ulcers hurt.

smoke brings toxins to your lungs, tar coats your lungs and the Alveoli in the lungs, leaving residue and clogging the alveoli making it harder to breath pure air, hence wheezing starts. and mucous builds up to try to rid the residue, so people cough up black soot in their sputum. Cancer likes the acid in nicotine and tar and it likes the acid environment, create a healthy environment and cancer cannot exist.