Can you still have lyme with negative spinal and blood test?

Yes, it is possible to still have Lyme disease even if spinal and blood tests return negative results. Lyme disease can be challenging to diagnose due to the variability in testing accuracy and the timing of the tests, as antibodies may not be present in the early stages of infection. Additionally, some individuals may not mount a strong immune response, leading to negative test results despite having the disease. If Lyme disease is suspected based on symptoms and potential exposure, a healthcare provider may consider a clinical diagnosis or recommend further testing.