Is V4 engine more nimble than V6 engine?

This depends on the vehicle year, make and model. In general, the V4 engine will have slower, less rapid acceleration than a V6. The V6 engine has more cylinders than a V4 capable of delivering more acceleration power to the engine. It is also important to note that a vehicle with more miles on the odometer will accelerate better than a brand new vehicle. The older vehicle is more "broken in" and will have a stronger acceleration and go.