Lubricants are added to tablet formulations primarily to reduce friction between the die wall and granules as the tablet is formed and ejected (Sprowl, 1974; Lachman et al., 1970). The other main activities attributed to a lubricant are: (a) prevention of sticking of granules to the tooling-anti-adherent; and (b) improvement of granule flow properties-glidant (Lachman et al., 1970). A given lubricant may provide one or more of these actions to varying degrees but no one material is highly efficient in all categories (Sperandeo and De Machi, 1976; Strickland, 1959; Sprowl, 1974).
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