Kartagener's syndrome is a rare genetic disorder characterized by a triad of symptoms: situs inversus (reversal of internal organs), chronic sinusitis, and bronchiectasis (abnormal dilation of the bronchi). It is caused by defects in the genes responsible for the structure and function of cilia, leading to impaired mucociliary clearance. This condition can result in respiratory infections and fertility issues due to immotile sperm. Diagnosis often involves imaging studies and genetic testing.
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