Can you give a dog tramadol and aspirin?

No - you should never give a dog aspirin or any other human over-the-counter pain medication (Tylenol, Advil, Aleve, ibuprofin, Motrin, etc.). Dogs are extremely sensitive to the side effects of these drugs and even one pill can be enough to cause a fatal stomach ulcer.

Prednisone is a powerful drug that is only given with a veterinarian's prescription. Overdosing can be fatal with this drug as well.