Actifed contains two main ingredients: an antihistamine (triprolidine or chlorpheniramine) and a decongestant (pseudoephedrine). The antihistamine component is primarily responsible for drowsiness, with triprolidine typically causing more sedation than chlorpheniramine. Therefore, formulations of Actifed that contain triprolidine are likely to make you feel sleepier. Always consult a healthcare professional before using any medication, especially for sleep-related concerns.
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