A bacteriophage on an E. coli culture plate typically appears as clear spots or plaques among the bacterial lawn. These plaques result from the lysis of E. coli cells, indicating areas where the bacteriophage has successfully infected and destroyed the bacteria. The size and number of plaques can vary depending on the bacteriophage strain and its efficiency in infecting the E. coli. The surrounding bacterial growth remains turbid, contrasting with the clear plaque areas.
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