How did Kary Mullis discover PCR?

Kary Mullis discovered the polymerase chain reaction (PCR) technique in 1983 while working as a biochemist at Cetus Corporation. He envisioned a method to amplify specific DNA sequences using cycles of heating and cooling to separate DNA strands and facilitate enzyme-driven replication. His innovative approach utilized Taq polymerase, a heat-stable enzyme from thermophilic bacteria, allowing for efficient DNA amplification. This breakthrough revolutionized molecular Biology, enabling numerous applications in research, medicine, and forensic science.