The integumentary system has a variety of functions; it may serve to waterproof, cushion and protect the deeper tissues, excrete wastes, regulate temperature and is the attachment site for sensory receptors to detect pain, sensation, pressure and temperature. In humans the integumentary system additionally provides vitamin D synthesis.
The integumentary system is the largest organ system. It distinguishes, separates, protects and informs the animal with regard to its surroundings. Small-bodied invertebrates of aquatic or continually moist habitats respire using the outer layer (integument). This gas exchange system, where gases simply diffuse into and out of the interstitial fluid, is called integumentary exchange.
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