Can you use 2 stroke fuel on a 4 stroke engine?

Two stroke fuel uses the same gasoline but has had oil added to lubricate the internal engine parts of a 2 stroke engine which does not have oil in a sump to lubricate the engine like a 4 stroke.

If you put this mix into a 4 stroke engine it will make a great deal of smoke and foul the spark plug, causing the engine to stop running. No permanent damage but definitely not recommended.