What is the significance of Teferi, Time Raveler's interaction with Nexus of Fate in the current Standard metagame?

In the current Standard metagame, Teferi, Time Raveler's ability to prevent opponents from casting instant spells at instant speed disrupts the strategy of using Nexus of Fate to take extra turns. This interaction is significant because it limits the effectiveness of decks that rely on Nexus of Fate to gain an advantage by taking multiple turns in a row.